Highlights • Intestinal Surf4 knockout mice recapitulate the phenotypes of chylomicron retention disease. • SURF4 regulates intestinal lipid secretion by mediating the transport of apolipoproteins PRAP1, ApoA1, and ApoB48. • Female Surf4 heterozygous mice are resistant to high-fat diet-induced hypercholesterolemia.
All Keywords
【저자키워드】 Apolipoprotein, small intestine, lipoprotein, Lipid absorption, Lipid secretion, SURF4,
【저자키워드】 Apolipoprotein, small intestine, lipoprotein, Lipid absorption, Lipid secretion, SURF4,