In COVID‐19 patients, neurological symptoms and complications are increasingly recognised, but their underlying causes remain poorly understood. This study found that SARS‐CoV‐2‐associated T cells were present in various brain regions of patients who had fatal COVID‐19 pneumonia, with the olfactory bulb, medulla and cerebellum showing the most specific patterns. These T cells primarily consisted of CD8^{+} T cells and were localised around blood vessels. Further research is required to fully understand the connection between T‐cell infiltration in the brain and its impact on patients’ cognitive and mental health in the long term.
All Keywords
【저자키워드】 COVID‐19, SARS‐CoV‐2, Neuroinflammation, Central nervous system, TCR sequencing, COVID‐19‐specific T cell,
【저자키워드】 COVID‐19, SARS‐CoV‐2, Neuroinflammation, Central nervous system, TCR sequencing, COVID‐19‐specific T cell,