Yang and colleagues demonstrate that SARS-CoV-2 can infect hPSC-derived midbrain dopamine (DA) neurons and induce cellular senescence. Several drug candidates were identified to rescue SARS-CoV-2 infection and DA neuron senescence. Inflammation and cellular senescence were also identified in substantia nigra tissue of COVID-19 patients.
All Keywords
【저자키워드】 SARS-CoV-2, senescence, human pluripotent stem cells, Dopaminergic neuron,
【저자키워드】 SARS-CoV-2, senescence, human pluripotent stem cells, Dopaminergic neuron,