Simple Summary This systematic review investigates the diagnostic concordance, advantages, and barriers of teledermatology in comparison to face-to-face dermatology for the diagnosis, management plan, and follow-up of non-melanoma skin cancer. Factors of increasing its sensitivity (teledermoscopy, quality of images, artificial intelligence, experience in generating clinical and teledermoscopy images) and its role as a tool for non-melanoma skin cancer triage for both underserved and high-risk populations are discussed. Abstract Background: Teledermatology is employed in the diagnosis and follow-up of skin cancer and its use was intensified during and after the COVID-19 pandemic. At the same time, demographic changes result in an overall increase in non-melanoma skin cancer and skin precancerous lesions. The aim of this study was to elucidate the role of teledermatology in comparison to conventional face-to-face dermatology for such lesions and determine the advantages and limitations of this workflow for patients and physicians. Methods: Research was performed using relevant keywords in MEDLINE and CENTRAL. Relevant articles were chosen following a predetermined standardized extraction form. Results: Diagnostic accuracy and interrater/intrarater agreement can be considered comparable—although lower—than in-person consultation. Improvement of particular features such as image quality, medical history availability, and teledermoscopy can further increase accuracy. Further aspects of limitations and advantages (mean time-to-assessment, time-to-treatment, cost-effectiveness) are discussed. Conclusions: Teledermatology has comparable diagnostic accuracy with face-to-face dermatology and can be utilized both for the effective triage of non-melanocytic epithelial tumors and precancerous lesions, as well as the follow-up. Easy access to dermatologic consultation with shorter mean times to diagnostic biopsy and/or treatment coupled with cost-effectiveness could compensate for the lower sensitivity of teledermatology and offer easier access to medical care to the affected populations.
【저자키워드】 Diagnosis, teledermatology, Squamous cell carcinoma, basal cell carcinoma, Non-melanoma skin cancer,