Push forward LC-MS-based therapeutic drug monitoring and pharmacometabolomics for anti-tuberculosis precision dosing and comprehensive clinical management

Published on
Journal: Journal of Pharmaceutical Analysis
[저자] Nguyen Quang Thu, Nguyen Tran Nam Tien, Nguyen Thi Hai Yen, Thuc-Huy Duong, Nguyen Phuoc Long, Huy Truong Nguyen
[Category] update2024,
PMC URL    Pubmed URL    DOI URL    [DOI] 10.1016/j.jpha.2023.09.009    
[Article Type] Review Paper
[Source] PMC

Highlights • LC–MS facilitates routine TDM and pharmacometabolomics toward precision dosing. • LC–MS-based bioassay methods of anti-TB drugs and metabolites was summarized. • Perspectives on numerous advancements in TB management were highlighted. • Comprehensive approach was proposed to enhance clinical outcomes and eradicate TB.

All Keywords
【저자키워드】 Tuberculosis, precision medicine, LC-MS, Therapeutic Drug Monitoring, MIPD, Pharmacometabolomics,