The immunobiology regulating the contribution of monocytes to severe COVID-19 immunopathology are not fully understood. Here the authors show that SARS-CoV-2 S1 and NP proteins differentially promote NLRP3/NLRC4 inflammasome activity, differentiation, and T cell-priming function of monocytes.
All Keywords
【저자키워드】 SARS-CoV-2, viral infection, Monocytes and macrophages, Inflammasome,
【저자키워드】 SARS-CoV-2, viral infection, Monocytes and macrophages, Inflammasome,