The critical contribution of the lectin activation pathway of complement to life-threatening systemic inflammation is shown in a murine model of SARS-CoV-2 infection. Inhibition of the lectin pathway key enzyme MASP-2 protects from the fatal outcome of severe inflammatory disease.
All Keywords
【저자키워드】 COVID-19, SARS-CoV-2, ARDS, complement system, lectin pathway,
【저자키워드】 COVID-19, SARS-CoV-2, ARDS, complement system, lectin pathway,