A signal transmission strategy driven by gap-regulated exonuclease hydrolysis for hierarchical molecular networks

Published on
Journal: Communications Biology
[저자] Xin Liu, Xun Zhang, Shuang Cui, Shujuan Xu, Rongming Liu, Bin Wang, Xiaopeng Wei, Qiang Zhang
[Category] update2024,
PMC URL    Pubmed URL    DOI URL    [DOI] 10.1038/s42003-024-06036-5    
[Article Type] Article
[Source] PMC

A signal transmission strategy, based on the cooperative activities of Exonuclease III and Exonuclease lambda enzymes, generates discrete and tightly amplified DNA signals that overcome signal attenuation and resolve the polarity of signals and byproducts.

All Keywords
【저자키워드】 Enzyme mechanisms, DNA, Synthetic biology, Hydrolases,