In this study, we adopted a two‐stage study design to explore the associations between single nucleotide polymorphisms (SNPs) in the Notch pathway genes and the survival of HBV‐related hepatocellular carcinoma (HCC) patients. We found three independent SNPs (NEURL1B rs4868192 T>C, CNTN1 rs444927 G>A, and FCER2 rs1990975 C>T) were significantly associated with the OS of HBV‐related HCC, which may serve as potential prognostic biomarkers. Our study could provide reference for improving the survival of HCC.
All Keywords
【저자키워드】 survival, Single nucleotide polymorphism, Hepatitis B virus, Hepatocellular carcinoma, notch signaling pathway,
【저자키워드】 survival, Single nucleotide polymorphism, Hepatitis B virus, Hepatocellular carcinoma, notch signaling pathway,