Repeat vaccination with COVID-19 mRNA vaccines has been shown to increase breadth of the antibody response. Here the authors demonstrate that B cell clones induced by the ancestral COVID-19 vaccine develop into daughter clones with different reactivity to individual SARS-CoV-2 variants through the accumulation of somatic hypermutations.
All Keywords
【저자키워드】 antibodies, SARS-CoV-2, RNA vaccines, Somatic hypermutation,
【저자키워드】 antibodies, SARS-CoV-2, RNA vaccines, Somatic hypermutation,