Temporal blockade of the mononuclear phagocyte system is an approach to enhance the therapeutic efficiency of nanocarrier drug-delivery systems but the broad applicability is hindered by the complexity of optimisation and management of potential side effects. Here, the authors review the development of this technique and show its efficiency using meta-analysis of the published data and discuss essential features for its successful translation to clinic.
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【저자키워드】 Biomedical materials, drug delivery, Nanoscale biophysics, Organic molecules in materials science,
【저자키워드】 Biomedical materials, drug delivery, Nanoscale biophysics, Organic molecules in materials science,