Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has caused several problems in healthcare systems around the world, as to date, there is no effective and specific treatment against all forms of COVID-19. Currently, drugs with therapeutic potential are being tested, including antiviral, anti-inflammatory, anti-malarial, immunotherapy, and antibiotics. Although antibiotics have no direct effect on viral infections, they are often used against secondary bacterial infections, or even as empiric treatment to reduce viral load, infection, and replication of coronaviruses. However, there are many concerns about this therapeutic approach as it may accelerate and/or increase the long-term rates of antimicrobial resistance (AMR). We focused this overview on exploring candidate drugs for COVID-19 therapy, including antibiotics, considering the lack of specific treatment and that it is unclear whether the widespread use of antibiotics in the treatment of COVID-19 has implications for the emergence and transmission of multidrug-resistant bacteria.
【저자키워드】 COVID-19, SARS-CoV-2, antimicrobial resistance, Multidrug-resistant bacteria, 【초록키워드】 Treatment, severe acute respiratory syndrome coronavirus 2, Coronaviruses, coronavirus, therapy, Anti-inflammatory, Antiviral, Immunotherapy, Infection, Antibiotics, Transmission, drug, severe acute respiratory syndrome Coronavirus, viral infections, antimicrobial resistance, Replication, Viral, Viral load, Bacteria, COVID-19 therapy, Secondary bacterial infections, respiratory, Bacterial infections, Therapeutic approach, Healthcare system, Healthcare systems, acute respiratory syndrome, acute respiratory syndrome coronavirus, therapeutic potential, problem, candidate drugs, specific treatment, widespread, multidrug-resistant, implication, effective, tested, lack, caused, form, reduce, accelerate, candidate drug, use of antibiotics, 【제목키워드】 pandemic, antibiotic, administration, treatment for COVID-19,