Yang et al. structurally characterize antibody responses to H2N2 vaccination in H2-naive and H2-exposed people, demonstrating temporal immune biases to conserved and variable regions on HA. H2N2 vaccination elicited antibodies to conserved sites on the HA stem, receptor-binding site, and medial junction.
All Keywords
【저자키워드】 neutralizing antibody, Influenza, hemagglutinin, cryo-EM, monoclonal, polyclonal, structure-based vaccine design, H2, medial junction,
【저자키워드】 neutralizing antibody, Influenza, hemagglutinin, cryo-EM, monoclonal, polyclonal, structure-based vaccine design, H2, medial junction,