Genetic testing is crucial for precision cancer medicine. Here, the authors develop a one-pot ERA-CRISPR assay to detect variable same-site indels, using an engineered AsCas12a variant with improved mismatch tolerance and broadened PAM scope.
All Keywords
【저자키워드】 Cancer screening, Genetic testing, CRISPR-Cas systems, Genotyping and haplotyping,
【저자키워드】 Cancer screening, Genetic testing, CRISPR-Cas systems, Genotyping and haplotyping,