Bats are remarkably tolerant to viral infections and their unique immune system, characterized by high level of tissue protection and dampened inflammatory responses, contributes to their longevity. Here authors show that the diversity of the bat antibody repertoire changes according to the body temperature and metabolic activity of the animals and higher activity directs their specificity towards eliminating damaged epithelial and endothelial cells.
All Keywords
【저자키워드】 antibodies, Inflammation, molecular evolution, Animal physiology,
【저자키워드】 antibodies, Inflammation, molecular evolution, Animal physiology,