New perspectives on the therapeutic potential of quercetin in non-communicable diseases: Targeting Nrf2 to counteract oxidative stress and inflammation

Published on
Journal: Journal of Pharmaceutical Analysis
[저자] Li Zhang, Li-Yue Xu, Fei Tang, Dong Liu, Xiao-Lan Zhao, Jing-Nan Zhang, Jia Xia, Jiao-Jiao Wu, Yu Yang, Cheng Peng, Hui Ao
[Category] update2024,
PMC URL    Pubmed URL    DOI URL    [DOI] 10.1016/j.jpha.2023.12.020    
[Article Type] Review Paper
[Source] PMC

Highlights • Quercetin, a readily available flavonoid, shows promise in anti-NCDs by strongly binding to Nrf2. • Nrf2-targeted Quercetin demonstrates robust antioxidant and anti-inflammatory capabilities. • Quercetin modulates mitochondria, apoptosis, and autophagy by Nrf2, thereby enhancing its potential against NCDs.

All Keywords
【저자키워드】 Anti-inflammatory, quercetin, antioxidant, Nrf2, non-communicable diseases, availability,