Analysis of Clinical Samples of Pancreatic Cyst’s Lesions with A Multi‐Analyte Bioelectronic Simot Array Benchmarked Against Ultrasensitive Chemiluminescent Immunoassay

Published on
Journal: Advanced Science
[저자] Cecilia Scandurra, Kim Björkström, Mariapia Caputo, Lucia Sarcina, Enrico Genco, Francesco Modena, Fabrizio Antonio Viola, Celestino Brunetti, Zsolt M. Kovács‐Vajna, Cinzia Di Franco, Lena Haeberle, Piero Larizza, Maria Teresa Mancini, Ronald Österbacka, William Reeves, Gaetano Scamarcio, May Wheeler, Mario Caironi, Eugenio Cantatore, Fabrizio Torricelli, Irene Esposito, Eleonora Macchia, Luisa Torsi
[Category] update2024,
PMC URL    Pubmed URL    DOI URL    [DOI] 10.1002/advs.202308141    
[Article Type] Research Article
[Source] PMC

SiMoT‐Single‐Molecule with Large Transistor technology simultaneously analyzes protein and genetic markers, achieving a one‐molecule threshold in 0.1 mL. Benchmarking against SIMOA chemiluminescent ultrasensitive assay, SiMoT outperforms SIMOA in speed and overall performance. Moreover, SiMoT provides an electronic response, enhancing its suitability for direct digital data communication.

All Keywords
【저자키워드】 liquid biopsy, bioelectronic transistors, multivariate data processing, SIMOA‐single‐molecule‐array‐, SiMoT‐single‐molecule‐with‐a‐large‐transistor, single‐molecule biosensors,