An attenuated lymphocytic choriomeningitis virus vector enhances tumor control in mice partly via IFN-I

Published on 2024-06-112024-09-05
Journal: The World Allergy Organization Journal

[저자] Young Rock Chung, Bakare Awakoaiye, Tanushree Dangi, Nahid Irani, Slim Fourati, Pablo Penaloza-MacMaster

[Category] update2024,

PMC URL Pubmed URL DOI URL [DOI] 10.1172/JCI178945

[Article Type] Research Article

[Source] PMC

The antitumoral effects of lymphocytic choriomeningitis virus vectors that extend to Rag1^{–/–} and MyD88^{–/–} mice suggest involvement of multiple mechanisms, including IFN-1 responses.

All Keywords
【저자키워드】 immunology, Cancer immunotherapy, Adaptive immunity, Vaccines, Cellular immune response,