As the numbers of sexually transmitted infections are rising, innovative prophylactic measures are needed. Knapp et al. performed a medium-throughput compound screen to identify new drugs inhibiting Chlamydia trachomatis growth in cell lines. The top hits were tested in a Chlamydia trachomatis mouse model for their ability to prevent infection.
All Keywords
【저자키워드】 prevention, Antibacterial, mouse model, sexually transmitted infections, pre-exposure prophylaxis, Chlamydia trachomatis, compound screen, Neisseria gonorrhea,
【저자키워드】 prevention, Antibacterial, mouse model, sexually transmitted infections, pre-exposure prophylaxis, Chlamydia trachomatis, compound screen, Neisseria gonorrhea,