Antibody design still heavily relies on isolating antigen-specific antibodies from serum. Here the authors report a Pre-trained Antibody generative large Language Model (PALM-H3) for the de novo generation of artificial antibodies heavy chain complementarity-determining region 3 with desired antigen-binding specificity.
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【저자키워드】 bioinformatics, Computational biology and bioinformatics, Antibody generation,
【저자키워드】 bioinformatics, Computational biology and bioinformatics, Antibody generation,