Exercise mobilizes diverse antigen specific T-cells and elevates neutralizing antibodies in humans with natural immunity to SARS CoV-2

Published on
Journal: Brain, Behavior, & Immunity - Health
[저자] Forrest L. Baker, Tiffany M. Zúñiga, Kyle A. Smith, Helena Batatinha, Terese S. Kulangara, Michael D. Seckeler, Shane C. Burgess, Emmanuel Katsanis, Richard J. Simpson
[Category] update2024,
PMC URL    Pubmed URL    DOI URL    [DOI] 10.1016/j.bbih.2023.100600    
[Article Type] Full Length Article
[Source] PMC

Highlights • Exercise reliably mobilizes MHC I restricted SARS-CoV-2 specific T-cells. • Exercise mobilized SARS-CoV-2 T-cells recognized all major regions of the virus. • Exercise mobilized SARS-CoV-2 T-cells responded to mutations in the Spike protein. • Broad TCR-β diversity is maintained in exercise mobilized SARS-CoV-2 T-cells. • Exercise transiently elevates anti-RBD-1 neutralizing antibodies to SARS CoV-2.

All Keywords
【저자키워드】 physical activity, Epstein-Barr virus, TCR sequencing, Exercise immunology, SARS Specific T-cells, VSTs,