The catastrophic coronavirus disease 2019 (COVID-19) pandemic is currently a critical global issue. One well-known complication of COVID-19 in severe cases is acute kidney injury, but no research has given a description of its impact on the kidney in patients with mild symptoms. We explore the renal function changes in mild COVID-19 patients. This retrospective, single-center study included 27 participants with laboratory-detected severe acute respiratory syndrome coronavirus two (SARS-CoV-2) infection who were admitted to the Tri-Service General Hospital from 4 February to 26 May 2020 and analyzed their clinical features, radiological findings, and laboratory data. Data collected upon admission and discharge showed a median estimated glomerular filtration rate (eGFR) of 106.7 mL/min/1.732 m 2 and 112.2 mL/min/1.732 m 2 , respectively, with a p -value of 0.044. A correlation between renal function and the severity of infection was also found and was statistically significant upon admission. Patients with a lower lymphocyte count or higher C-reactive protein, neutrophil count, and neutrophil-to-lymphocyte ratio presented with a decreased eGFR during their early infection phase. The biomarkers (CRP and NLR) may be linked with dynamic changes of renal function in COVID-19 patients who are asymptomatic or have mild symptoms.
【저자키워드】 COVID-19, C-reactive protein, renal function, Neutrophil-to-lymphocyte ratio, Asymptomatic, 【초록키워드】 coronavirus disease, SARS-CoV-2, coronavirus, pandemic, Biomarker, Infection, CRP, Acute kidney injury, discharge, Clinical features, kidney, Lymphocyte count, Research, Patient, correlation, change, Admission, Critical, mild symptoms, glomerular filtration rate, NLR, retrospective, early infection, COVID-19 patient, acute respiratory syndrome, laboratory data, P -value, neutrophil count, participant, Severe case, single-center study, mild COVID-19 patients, Severity of infection, complication of COVID-19, radiological, catastrophic, analyzed, collected, median, changes in, statistically significant, 【제목키워드】 change, function, dynamic,