The COVID-19 disease can cause hypoxemic respiratory failure due to ARDS, requiring invasive mechanical ventilation. Although early studies reported that COVID-19-associated ARDS has distinctive features from ARDS of other causes, recent observational studies have demonstrated that ARDS related to COVID-19 shares common clinical characteristics and respiratory system mechanics with ARDS of other origins. Therefore, mechanical ventilation in these patients should be based on strategies aiming to mitigate ventilator-induced lung injury. Assisted mechanical ventilation should be applied early in the course of mechanical ventilation by considering evaluation and minimizing factors associated with patient-inflicted lung injury. Extracorporeal membrane oxygenation should be considered in selected patients with refractory hypoxia not responding to conventional ventilation strategies. This review highlights the current and evolving practice in managing mechanically ventilated patients with ARDS related to COVID-19.
【저자키워드】 COVID-19, mechanical ventilation, Lung injury, weaning, 【초록키워드】 ARDS, Respiratory failure, hypoxia, Clinical characteristics, Ventilation, observational study, COVID-19 disease, Patient, membrane, Respiratory system, Invasive mechanical ventilation, Extracorporeal, Oxygenation, Ventilator-induced lung injury, Factor, causes, hypoxemic, mitigate, feature, highlight, COVID-19-associated ARDS, Course, selected, reported, demonstrated, mechanically ventilated patient, 【제목키워드】 Mechanical, Point,