The Coronavirus disease 2019 (COVID-19) pandemic is caused by rapidly spreading pathogenic virus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that affects vast majority of population worldwide. Although, around 80% of the cases had mild infection but still remaining 20% had developed respiratory failure and dysfunction of other organs that necessitate urgent oxygen therapy or specific interventions. Therefore, it is imperative to establish novel prognostic approaches to screen patients at high-risk of developing severe complications. The primary focus of current research for COVID-19 is to discover safe and efficacious vaccine for prevention and effective treatment for better management of the patients to overcome the pandemic. To achieve this goal, it is imperative to have better understanding of the molecular pathways involved in the pathophysiology and progression of severe COVID-19. The surge for reliable diagnostics and therapeutics targets for COVID-19 highlighted the great potential of high-throughput approach like metabolomics which may enable the development of personalized medicine.
【저자키워드】 COVID-19, metabolomics, Diagnosis, therapeutic targets, severe disease, 【초록키워드】 Treatment, SARS-CoV-2, Coronavirus disease 2019, Vaccine, coronavirus, pandemic, Respiratory failure, severe COVID-19, progression, diagnostics, pathophysiology, management, Personalized medicine, Research, Patient, pathway, Oxygen therapy, target, molecular, prognostic, mild infection, Safe, dysfunction, acute respiratory syndrome, severe complications, pathogenic virus, Affect, approach, effective, caused, involved, the patient, majority, overcome, imperative, other organ, 【제목키워드】 diagnostic, therapeutic, target, approach, Potential,