Abstract While the ongoing COVID‐19 pandemic affirms an urgent global need for effective vaccines as second and third infection waves are spreading worldwide and generating new mutant virus strains, it has also revealed the importance of mitigating the transmission of SARS‐CoV‐2 through the introduction of restrictive social practices. Here, it is demonstrated that an architecturally‐ and chemically‐diverse family of nanostructured anionic polymers yield a rapid and continuous disinfecting alternative to inactivate coronaviruses and prevent their transmission from contact with contaminated surfaces. Operating on a dramatic pH‐drop mechanism along the polymer/pathogen interface, polymers of this archetype inactivate the SARS‐CoV‐2 virus, as well as a human coronavirus surrogate (HCoV‐229E), to the minimum detection limit within minutes. Application of these anionic polymers to frequently touched surfaces in medical, educational, and public‐transportation facilities, or personal protection equipment, can provide rapid and repetitive protection without detrimental health or environmental complications. In the presence of water, the low pH that develops on nanostructured anionic block polymers prepared as stand‐alone films or surface coatings successfully inactivates pathogenic coronaviruses such as SARS‐CoV‐2 by at least 99.9% in just a few minutes. This class of sulfonated materials serves as a new and expedient route to combat the transmission of disease.
【저자키워드】 antiviral materials, charged block polymers, microphase‐ordered materials, polyanions, thermoplastic elastomers, 【초록키워드】 coronavirus, pandemic, equipment, Infection, Transmission, Polymer, COVID‐19, SARS‐CoV‐2, polymers, Health, complications, application, disease, Strains, mechanism, Detection limit, mutant virus, Contact, detrimental, water, contact with, contaminated surfaces, Effective vaccines, SARS‐CoV‐2 virus, minutes, while, pathogenic coronaviruses, pathogenic coronavirus, Prevent, human coronavirus, develop, demonstrated, effective vaccine, anionic, sulfonated, 【제목키워드】 SARS‐CoV‐2, Rapid,