Delirium is a sign of deterioration of homeostasis and worse prognosis. The aim of this study was to investigate the frequency, risk factors and prognosis of delirium in patients with COVID-19 in a temporary acute setting hospital. A retrospective cohort analysis of data collected between October 2020 and February 2021 from two temporary acute care hospitals was performed. All consecutive hospitalized patients ≥18 years old with COVID-19 were included. An assessment of consciousness was carried out at least two times a day, including neurological examination. Delirium was identified through retrospective chart review according to DSM-5 criteria if present at least once during hospitalization. Analysis included 201 patients, 39 diagnosed with delirium (19.4%). Delirious patients were older ( p < 0.001), frailer ( p < 0.001) and the majority were male ( p = 0.002). Respiratory parameters were worse in this group with higher oxygen flow ( p = 0.013), lower PaO 2 ( p = 0.043) and higher FiO 2 ( p = 0.006). The mortality rate was significantly higher in patients with delirium (46.15% vs 3.70%, p < 0.001) with OR 17.212 ( p < 0.001) corrected for age and gender. Delirious patients experienced significantly more complications: cardiovascular (OR 7.72, p < 0.001), pulmonary (OR 8.79, p < 0.001) or septic (OR 3.99, p = 0.029). The odds of mortality in patients with COVID-19 presenting with delirium at any point of hospitalization were seventeen times higher.
【저자키워드】 SARS-CoV-2, coronavirus, Critical care, Mortality, outcome, delirium, impaired consciousness, 【초록키워드】 Prognosis, Hospitalization, hospital, risk factor, Deterioration, male, Patient, mortality rate, respiratory, Care, patients, homeostasis, retrospective, Frequency, Analysis, neurological, criteria, Older, worse prognosis, retrospective cohort, parameter, DSM-5, oxygen flow, collected, significantly more, carried, diagnosed, was performed, majority, hospitalized patient, significantly higher, presenting, age and gender, Delirious, PaO, patients with COVID-19, with COVID-19, 【제목키워드】 temporary,