(1) Background: Patients suffering from the novel coronavirus 2019 (COVID-19) disease could experience several extra-pulmonary involvements, including cardiovascular complications and liver injury. This study aims to evaluate the presence of cardiac and liver alterations in patients with post-acute COVID-19 syndrome using transthoracic echocardiography (TTE) and liver elastography (LE). (2) Methods: A total of 97 subjects recovering from COVID-19, attending the hospital’s specialized outpatient clinic for persisting symptoms at 3 to 11 weeks after the acute illness, were included in this study. They all had a basal COVID-19 assessment, and subsequently, a clinical evaluation, laboratory tests, TTE, and LE. (3) Results: considering the presence of pulmonary injury during COVID-19, patients were divided into two groups. Although none of them had altered systolic function, we evidenced pulmonary hypertension, diastolic dysfunction, increased liver stiffness, viscosity, and steatosis in around one-third of the patients, with significantly higher values in subjects with pulmonary injury compared to those without. (4) Conclusion: persisting symptoms characterizing the post-acute COVID-19 syndrome could be explained by residual cardiac and hepatic lesions, which were worse in more severe COVID-19 forms. These patients may be at risk of developing liver fibrosis and cardiac alterations and should be investigated in the first 12 weeks after the onset of the infection.
【저자키워드】 COVID-19, Inflammation, Cytokine storm, Liver injury, transthoracic echocardiography, cardiovascular alterations, liver elastography, 【초록키워드】 severe COVID-19, Infection, risk, Laboratory tests, Symptom, Novel coronavirus, clinical evaluation, Patient, pulmonary injury, disease, liver, patients, pulmonary hypertension, Liver fibrosis, dysfunction, outpatient clinic, cardiovascular complication, two groups, subject, alteration, lesions, syndrome, liver stiffness, acute illness, steatosis, forms, diastolic, evaluate, investigated, explained, significantly higher, evidenced, recovering from COVID-19, TTE, 【제목키워드】 cardiac, hepatic, Presence,