Abstract Background: The Corona Virus Disease 2019 (COVID-19) is a new acute respiratory infectious disease that has become a major global public health event. In China, the combination of Huashi Baidu Formula (HBF) and antiviral drugs is used in the clinical treatment of severe patients with new coronary pneumonia, but there is still a lack of evidence-based medical evaluation. Methods: We search for research in PubMed/MEDLINE, China National Knowledge Infrastructure (CNKI), Wanfang Database, VIP Database, Cochrane Library, Embase, China Biomedical Database (CBM), and Chinese Science Citation Database (CSCD). For “Huashi Baidu Formula” and “COVID-19,” we screened suitable articles without language restrictions on keywords, and recorded and analyzed the screened literature with RevMan 5.3 and STATA 14.2 software. Results: This systematic review and meta-analysis will evaluate the efficacy and safety of HBF combined with antiviral drugs in the treatment of COVID-19, and provide the rationality of clinical drug application. Conclusion: Our findings will provide references for clinical diagnosis and treatment and guidance programs for COVID-19. INPLASY registration number: INPLASY202080098.
【저자키워드】 COVID-19, Meta-analysis, protocol, antiviral drugs, systematic review, Huashi Baidu Formula, 【초록키워드】 Treatment, antiviral drug, China, Corona, Research, Efficacy and safety, Severe patient, Clinical diagnosis, Guidance, Combination, Clinical treatment, Science, Infrastructure, global public health, Chinese, Cochrane Library, article, Stata, CNKI, respiratory infectious disease, coronary pneumonia, Formula, citation, Baidu, analyzed, lack, evaluate, screened, recorded, CBM, VIP, 【제목키워드】 Treatment, antiviral drug, therapeutic efficacy, Formula, Baidu,