SARS-CoV-2 is a member of the subgenus Sarbecovirus and thus contains the genetic element s2m. We have extensively mined nucleotide data in GenBank in order to obtain a comprehensive list of s2m sequences both in the four virus families where s2m has previously been described and in other groups of organisms. Surprisingly, there seems to be a xenologue of s2m in a large number of insect species. The function of s2m is unknown, but our data show a very high degree of sequence conservation both in insects and in viruses and that the version of s2m found in SARS-CoV-2 has unique features, not seen in any other virus or insect strains.
All Keywords
【저자키워드】 COVID-19, Coronaviruses, Horizontal gene transfer, s2m, invertebrates, positive-sense ssRNA viruses, 【초록키워드】 SARS-CoV-2, Genetic, virus, Features, group, Strains, nucleotide, Sequence conservation, Organisms, GenBank, sequence, insect, described, virus, unique, 【제목키워드】 Genetic, the SARS-CoV-2 genome,
【저자키워드】 COVID-19, Coronaviruses, Horizontal gene transfer, s2m, invertebrates, positive-sense ssRNA viruses, 【초록키워드】 SARS-CoV-2, Genetic, virus, Features, group, Strains, nucleotide, Sequence conservation, Organisms, GenBank, sequence, insect, described, virus, unique, 【제목키워드】 Genetic, the SARS-CoV-2 genome,