Background : Establishing the diagnosis of COVID-19 and Pneumocystis jirovecii pulmonary coinfection is difficult due to clinical and radiological similarities that exist between the two disorders. For the moment, fungal coinfections are underestimated in COVID-19 patients. Case presentation : We report the case of a 52-year-old male patient, who presented to the emergency department for severe dyspnea and died 17 h later. The RT-PCR test performed at his admission was negative for SARS-CoV-2. Retesting of lung fragments collected during autopsy revealed a positive result for SARS-CoV-2. Histopathological examination showed preexisting lesions, due to comorbidities, as well as recent lesions: massive lung thromboses, alveolar exudate rich in foam cells, suprapleural and intra-alveolar Pneumocystis jirovecii cystic forms, and bilateral adrenal hemorrhage. Conclusion : COVID-19 and P. jirovecii coinfection should be considered, particularly in critically ill patients, and we recommend the systematic search for P. jirovecii in respiratory samples.
【저자키워드】 COVID-19, SARS-CoV-2, Pneumonia, Autopsy, Coinfection, Pneumocystis jirovecii, 【초록키워드】 Comorbidities, lung, Dyspnea, male, Patient, Respiratory samples, Admission, fungal, critically ill patients, COVID-19 patients, RT-PCR test, similarity, foam cells, disorders, positive result, lesions, histopathological examination, forms, alveolar, radiological, performed, collected, died, adrenal hemorrhage, diagnosis of COVID-19, Establishing, intra-alveolar, 【제목키워드】 pulmonary, Confirmed,