Approximately 67% of U.S. households have pets. Limited data are available on SARS-CoV-2 in pets. We assessed SARS-CoV-2 infection in pets during a COVID-19 household transmission investigation. Pets from households with ≥1 person with laboratory-confirmed COVID-19 were eligible for inclusion from April–May 2020. We enrolled 37 dogs and 19 cats from 34 households. All oropharyngeal, nasal, and rectal swabs tested negative by rRT-PCR; one dog’s fur swabs (2%) tested positive by rRT-PCR at the first sampling. Among 47 pets with serological results, eight (17%) pets (four dogs, four cats) from 6/30 (20%) households had detectable SARS-CoV-2 neutralizing antibodies. In households with a seropositive pet, the proportion of people with laboratory-confirmed COVID-19 was greater (median 79%; range: 40–100%) compared to households with no seropositive pet (median 37%; range: 13–100%) ( p = 0.01). Thirty-three pets with serologic results had frequent daily contact (≥1 h) with the index patient before the person’s COVID-19 diagnosis. Of these 33 pets, 14 (42%) had decreased contact with the index patient after diagnosis and none were seropositive; of the 19 (58%) pets with continued contact, four (21%) were seropositive. Seropositive pets likely acquired infection after contact with people with COVID-19. People with COVID-19 should restrict contact with pets and other animals.
【저자키워드】 COVID-19, zoonoses, SARS-CoV-2, Transmission, dog, pets, cat, household transmission, 【초록키워드】 SARS-COV-2 infection, Infection, Diagnosis, nasal, rRT-PCR, Patient, COVID-19 diagnosis, Households, Oropharyngeal, Swab, seropositive, SARS-CoV-2 neutralizing antibodies, Contact, contact with, Laboratory-confirmed COVID-19, positive, laboratory-confirmed, serological results, rectal swab, greater, enrolled, tested, proportion, detectable, eight, median, restrict, eligible, for inclusion, Limited, people with COVID-19, with COVID-19, 【제목키워드】 Human, household, one health, Seropositivity, investigation, Confirmed,