Abstract Background Geriatric patients with coronavirus disease (COVID‐19) are at high risk of developing cardiac injury. Identifying the factors that affect high‐sensitivity cardiac troponin I may indicate the cause of cardiac injury in elderly patients, and this could hopefully assist in protecting heart function in this patient population. Methods One hundred and eighty inpatients who were admitted for COVID‐19 were screened. Patients older than 60 years were included in this study, and the clinical characteristics and laboratory results of the cohort were analyzed. The correlation between cardiac injury and clinical/laboratory variables was statistically analyzed, and further logistic regression was performed to determine how these variables influence cardiac injury in geriatric patients. Results Age ( p < 0.001) significantly correlated with cardiac injury, whereas sex ( p = 0.372) and coexisting diseases did not. Rising procalcitonin ( p = 0.001), interleukin‐2 receptor ( p < 0.001), interleukin 6 ( p = 0.001), interleukin 10 ( p < 0.001), tumor necrosis factor α ( p = 0.001), high‐sensitivity C‐reactive protein ( p = 0.001), D‐dimer ( p < 0.001), white blood cells ( p < 0.001), neutrophils ( p = 0.001), declining lymphocytes ( p < 0.001), and natural killer cells ( p = 0.005) were associated with cardiac injury and showed predictive ability in the multivariate logistic regression. Conclusion Our results suggest that age and inflammatory factors influence cardiac injury in elderly patients. Interfering with inflammation in this patient population may potentially confer cardiac protection. Our study explored potential risk factors related to cardiac injury in elderly patients with COVID‐19. The results suggest that age and inflammatory factors influence cardiac injury in elderly patients. Interfering with inflammation in this patient population may potentially confer cardiac protection.
【저자키워드】 Inflammation, COVID‐19, troponin, cardiac injury, Elderly patient, 【초록키워드】 coronavirus disease, Necrosis, Clinical characteristics, neutrophil, Sex, procalcitonin, elderly patients, COVID‐19, cardiac troponin, lymphocyte, Cohort, White blood cell, Patient, Logistic regression, age, receptor, correlation, disease, patients, natural killer cell, Injury, D‐dimer, high risk, Predictive, Inpatient, Older, Factor, potential risk, multivariate logistic regression, C‐reactive protein, patient population, identifying, variable, Inflammatory factor, Affect, Result, analyzed, significantly, was performed, screened, determine, correlated, assist, statistically, declining, laboratory result, 【제목키워드】 COVID‐19 patient,