Background The job environment has changed a lot during the period of the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to investigate the association between work-related stress and aggravation of pre-existing disease in workers during the first state of COVID-19 emergency in Japan. Methods Data were obtained from a large internet survey conducted between August 25 and September 30, 2020 in Japan. Participants who reported that they had a job as well as current history of disease(s) (ie, pre-existing conditions) were included ( n = 3,090). Aggravation of pre-existing disease during the state of emergency was self-reported. Work-related stress from April 2020 (since the state of COVID-19 emergency) was assessed according to a job demand–control model. Multivariable logistic regression models were used to analyze the association. Results Aggravation of pre-existing diseases was reported by 334 participants (11%). The numbers of participants with high demand and low control were 112 (18%) and 100 (14%), respectively. Compared to medium demand, high demand was significantly associated with aggravation of pre-existing diseases (odds ratio 1.77; 95% confidence interval, 1.30–2.42). Low control compared to medium control was also significantly associated with aggravation of pre-existing diseases (odds ratio 1.39; 95% confidence interval, 1.02–1.92). Conclusion Work-related stress during the first state of COVID-19 emergency was associated with aggravation of pre-existing disease during that period.
【저자키워드】 COVID-19, Work-related stress, job control, pre-existing disease, job demand, 【초록키워드】 coronavirus disease, pandemic, Stress, Japan, aggravation, disease, association, Odds ratio, 95% confidence interval, medium, logistic regression model, participant, COVID-19 emergency, Result, significantly, reported, conducted, were used, changed, conditions, 【제목키워드】 Model, Japan, aggravation, Emergency, state,