Pets play a crucial role in the development of human feelings, social life, and care. However, in the era of the prevailing global pandemic of COVID-19 disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many questions addressing the routes of the virus spread and transmission to humans are dramatically emerging. Although cases of SARS-CoV-2 infection have been found in pets including dogs, cats, and ferrets, to date there is no strong evidence for pet-to-human transmission or sustained pet-to-pet transmission of SARS-CoV-2. However, an increasing number of studies reporting detection of SARS-CoV-2 in farmed minks raises suspicion of potential viral transmission from these animals to humans. Furthermore, due to the high susceptibility of cats, ferrets, minks and hamsters to COVID-19 infection under natural and/or experimental conditions, these animals have been extensively explored as animal models to study the SARS-CoV-2 pathogenesis and transmission. In this review, we present the latest reports focusing on SARS-CoV-2 detection, isolation, and characterization in pets. Moreover, based on the current literature, we document studies aiming to broaden the knowledge about pathogenicity and transmissibility of SARS-CoV-2, and the development of viral therapeutics, drugs and vaccines. Lastly, considering the high rate of SARS-CoV-2 evolution and replication, we also suggest routes of protection against the virus.
【저자키워드】 COVID-19, SARS-CoV-2, pets suitable animal models, zoonotic potential, 【초록키워드】 coronavirus, Pathogenesis, Vaccines, hamsters, knowledge, SARS-COV-2 infection, susceptibility, Human, Transmission, animal model, drug, animal models, severe acute respiratory syndrome Coronavirus, virus, COVID-19 disease, Replication, global pandemic, SARS-CoV-2 detection, Viral, Transmissibility, COVID-19 infection, cats, humans, Isolation, SARS-CoV-2 evolution, Viral transmission, hamster, respiratory, pathogenicity, Care, SARS-CoV-2 pathogenesis, Evidence, life, characterization, acute respiratory syndrome, acute respiratory syndrome coronavirus, acute respiratory syndrome coronavirus 2, virus spread, ferrets, suspicion, transmissibility of SARS-CoV-2, transmission of SARS-CoV-2, raise, caused, question, conditions, sustained, the SARS-CoV-2, 【제목키워드】 role, state, current,