Aim: Evaluating the incidence and course of COVID-19 in cancer patients treated with immunotherapy. Patients & methods: We reported the influenza-like illness events with diagnosis of COVID-19 within the patient cohort enrolled in the prospective observational multicenter INVIDIa-2 study in the single center of Parma. Results: Among 53 patients, eight experienced influenza-like illness during the influenza season 2019/2020, and three of them had diagnosis of COVID-19. They were males, elderly, with cardiovascular disease. Radiological features of COVID-19 pneumonitis were found in all of three cases, although the pharyngeal swab resulted positive in only two. Two of these three patients died due to respiratory failure. Conclusion: Cancer patients are at high risk of severe events from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
【저자키워드】 COVID-19, SARS-CoV2, Immunotherapy, influenza vaccine, Cancer patients, interstitial pneumonia, Anti-PD-1, Immune checkpoint inhibitors, 【초록키워드】 SARS-CoV-2, coronavirus, Respiratory failure, Influenza, Infection, cardiovascular disease, Cohort, Patient, incidence, multicenter, patients, high risk, cancer patient, Pharyngeal swab, acute respiratory syndrome, positive, feature, event, males, Course, enrolled, reported, the patient, eight, treated, diagnosis of COVID-19, Evaluating, patients died, 【제목키워드】 Prospective Study, Cohort, clinical, cancer patient, single-center, receiving,