Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), has been demonstrated to be able to activate complement, making patients with deficiency in negative complement regulation, such as paroxysmal nocturnal hemoglobinuria (PNH), particularly vulnerable to complement-mediated cell damage. We report a case of a patient who presented with fatigue, facial swelling, and upper respiratory infection (URI) symptoms and was found to have COVID-19 with laboratory tests showing severe hemolysis and pancytopenia secondary to PNH.
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【초록키워드】 COVID-19, coronavirus disease, SARS-CoV-2, coronavirus, fatigue, complement, Symptom, virus, Hemolysis, Patient, Laboratory test, paroxysmal nocturnal hemoglobinuria, deficiency, acute respiratory syndrome, Regulation, upper respiratory infection, cell damage, demonstrated, cause, activate, facial, 【제목키워드】 COVID-19, hemoglobinuria,
【초록키워드】 COVID-19, coronavirus disease, SARS-CoV-2, coronavirus, fatigue, complement, Symptom, virus, Hemolysis, Patient, Laboratory test, paroxysmal nocturnal hemoglobinuria, deficiency, acute respiratory syndrome, Regulation, upper respiratory infection, cell damage, demonstrated, cause, activate, facial, 【제목키워드】 COVID-19, hemoglobinuria,