Bacterial coinfections are not uncommon with respiratory viral pathogens. These coinfections can add to significant mortality and morbidity. We are currently dealing with the SARS-CoV-2 pandemic, which has affected over 15 million people globally with over half a million deaths. Previous respiratory viral pandemics have taught us that bacterial coinfections can lead to higher mortality and morbidity. However, there is limited literature on the current SARS-CoV-2 pandemic and associated coinfections, which reported infection rates varying between 1% and 8% based on various cross-sectional studies. In one meta-analysis of coinfections in COVID-19, rates of Streptococcus pneumoniae coinfections have been negligible when compared to previous influenza pandemics. Current literature does not favor the use of empiric, broad-spectrum antibiotics in confirmed SARS-CoV-2 infections. We present three cases of confirmed SARS-CoV-2 infections complicated by Streptococcus pneumoniae coinfection. These cases demonstrate the importance of concomitant testing for common pathogens despite the need for antimicrobial stewardship.
【초록키워드】 COVID-19, Meta-analysis, pandemic, Mortality, Influenza, SARS-COV-2 infection, SARS-CoV-2 pandemic, Antibiotics, pathogen, morbidity, Pandemics, Pathogens, infection rate, Cross-sectional studies, SARS-CoV-2 infections, Streptococcus pneumoniae, deaths, Bacterial coinfection, favor, respiratory viral, current, affected, reported, the SARS-CoV-2, 【제목키워드】 Coinfection, Streptococcus pneumoniae, Sery,