COVID-19 pandemic has already produced great impacts on global health security and social-economy. Elderly, particularly those with underlying diseases, are suffering from higher fatality rate. Neurodegenerative diseases are a group of incurable neurological disorders of loss of neuron and/or myelin sheath, which affect hundreds of millions of elderly populations and usually need long-term care. Older population is one of the most vulnerable to COVID-19 pandemic. In this report, we reviewed the current status of COVID-19 on the patients with several neurodegenerative diseases, particularly Alzheimer’s disease, Parkinson’s disease, prion disease, and amyotrophic lateral sclerosis. Meanwhile, the potential mechanisms of SARS-CoV-2 infection in the pathogenesis of neurodegenerative diseases were also summarized.
【저자키워드】 Coronavirus disease 2019, Parkinson’s disease, Amyotrophic lateral sclerosis, Severe Acute Respiratory Syndrome-associated Coronavirus 2, Alzheimer’s disease (AD), Creutzfeldt-Jakob disease, 【초록키워드】 COVID-19, Diseases, Pathogenesis, SARS-COV-2 infection, COVID-19 pandemic, elderly, Population, Alzheimer’s disease, Impact, underlying diseases, disease, Care, global health security, Neurological disorder, Parkinson’s disease, potential mechanism, Fatality rate, Affect, produced, the patient, incurable, neurodegenerative, myelin sheath, 【제목키워드】 COVID-19, Impact,