Objectives: The aim of this study was to correlate the clinical, laboratory, and radiographic characteristics of patients with a confirmed diagnosis of coronavirus disease 2019 (COVID-19) disease, with fatal outcome. Methods: We reviewed chest X-ray (CXR) features, clinical, and laboratory data of patients with reverse transcriptase polymerase-chain-reaction confirmed diagnosis of COVID-19 infection. The relationship with mortality was investigated by fitting a logistic regression model. Results: A total of 246 patients were included (170 males; mean age, 63 y). Most of the patients had 1 or more comorbidity (62%); fever (95%), and cough (60%) were the most common symptoms; CXR detected abnormalities in 88.6%, mainly showing ground-glass opacities (GGO) (90%) with bilateral (64%) and peripheral (46%) distribution. Multivariate analysis showed that age ( P < 0.001; mortality of 59% in patients >66 y old; 5% at a younger age) and consolidation at CXR ( P = 0.001; mortality of 11% with positive CXR; 2% in those without) represented the 2 most significant independent risk factors of mortality. Chronic pathologies, such as diabetes and chronic obstructive pulmonary disease, and peripheral GGO at CXR also showed a significant correlation with mortality. Conclusions: We identified predictive factors for the fatal outcome of COVID-19 patients. The prognostic value of these findings can be useful for optimal patient management and resource allocation.
【저자키워드】 COVID-19, coronavirus disease, Pneumonia, Viral, Radiography, patient outcome assessment, 【초록키워드】 Mortality, Infection, Diagnosis, Comorbidity, outcome, cough, Laboratory, ground-glass opacity, Features, management, Fever, Patient, age, chest X-ray, GGO, correlation, distribution, Pathologies, resource, disease, consolidation, COVID-19 patients, pulmonary disease, Multivariate analysis, CXR, chronic, Predictive, Prognostic value, Factor, laboratory data, logistic regression model, Radiographic, independent risk factor, positive, abnormality, transcriptase, MOST, the patient, investigated, diabete, chronic obstructive, characteristics of patient, diagnosis of COVID-19, 【제목키워드】 Factor,