Recent evidence indicates that a large proportion of deaths from coronavirus disease 2019 (COVID-19) can be attributed to cardiovascular disease, including acute myocardial infarction, arrhythmias and heart failure. Indeed, severe infection increases the risk of heart failure among patients with COVID-19. In most patients, heart failure arises from complex interactions between pre-existing conditions, cardiac injury, renin-angiotensin system activation, and the effects of systemic inflammation on the cardiovascular system. In this review, we summarize current knowledge regarding pathogen-driven heart failure occurring during treatment for COVID-19, the potential effects of commonly used cardiovascular and anti-infective drugs in these patients, and possible directions for establishing a theoretical basis for clinical treatment.
【저자키워드】 COVID-19, cardiovascular disease, clinical outcomes, Therapeutic strategies, cardiac failure, Angiotensin (Ang)-converting enzyme 2, 【초록키워드】 coronavirus disease, Severe infection, knowledge, risk, cardiovascular system, arrhythmia, renin-angiotensin system, heart failure, death, systemic inflammation, patients, Evidence, Acute myocardial infarction, Injury, Clinical treatment, Activation, complex interaction, Effect, recent, proportion, indicate, increase, conditions, anti-infective drug, arise, patients with COVID-19, treatment for COVID-19, 【제목키워드】 cardiovascular, heart, failure, insight,