Hospital-acquired infections are emerging major concurrent conditions during the coronavirus disease (COVID-19) pandemic. We conducted a retrospective review of hospitalizations during March‒October 2020 of adults tested by reverse transcription PCR for severe acute respiratory syndrome coronavirus 2. We evaluated associations of COVID-19 diagnosis with risk for laboratory-confirmed bloodstream infections (LCBIs, primary outcome), time to LCBI, and risk for death by using logistic and competing risks regression with adjustment for relevant covariates. A total of 10,848 patients were included in the analysis: 918 (8.5%) were given a diagnosis of COVID-19, and 232 (2.1%) had LCBIs during their hospitalization. Of these patients, 58 (25%) were classified as having central line‒associated bloodstream infections. After adjusting for covariates, COVID-19‒positive status was associated with higher risk for LCBI and death. Reinforcement of infection control practices should be implemented in COVID-19 wards, and review of superiority and inferiority ranking methods by National Healthcare Safety Network criteria might be needed.
【저자키워드】 COVID-19, coronavirus disease, viruses, respiratory infections, zoonoses, SARS-CoV-2, infection control, Coronaviruses, pandemic, hospitalized patients, incidence, severe acute respiratory coronavirus 2, deaths, prone positioning, bloodstream infection risk, 【초록키워드】 coronavirus, Safety, Hospitalization, risk, Patient, COVID-19 diagnosis, death, network, covariates, reverse transcription PCR, bloodstream infection, patients, association, retrospective, Hospital-acquired infection, criteria, Bloodstream infections, Logistic, acute respiratory syndrome, Primary outcome, higher risk, reinforcement, laboratory-confirmed, tested, evaluated, conducted, condition, were given, competing, diagnosis of COVID-19,