Emerging concerns following the severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) pandemic are the long-term effects of coronavirus disease (COVID)-19. Dysgeusia in COVID-19 is supported by the abundant expression of the entry receptor, angiotensin-converting enzyme-2 (ACE2), in the oral mucosa. The invading virus perturbs the commensal biofilm and regulates the host responses that permit or suppress viral infection. We correlated the microbial recognition receptors and soluble ACE2 (sACE2) with the SARS-CoV2 measures in the saliva of COVID-19 patients. Data indicate that the toll-like receptor-4, peptidoglycan recognition protein, and sACE2 are elevated in COVID-19 saliva and correlate moderately with the viral load.
【저자키워드】 COVID-19, Saliva, health informatics, receptor, Taste, Innate, 【초록키워드】 viral infection, ACE2, SARS-CoV2, pandemic, host response, virus, dysgeusia, Viral load, angiotensin-converting enzyme-2, expression, COVID-19 patients, Coronavirus-2, soluble ACE2, regulate, microbial, Coronavirus Disease (COVID)-19, acute respiratory syndrome, measure, entry receptor, oral mucosa, sACE2, Effect, elevated, supported, correlated, suppress, recognition protein, 【제목키워드】 molecule, Can,