Severe acute respiratory syndrome coronavirus 2 viral load in the upper respiratory tract peaks around symptom onset and infectious virus persists for 10 days in mild-to-moderate coronavirus disease (n = 324 samples analysed). RT-PCR cycle threshold (Ct) values correlate strongly with cultivable virus. Probability of culturing virus declines to 8% in samples with Ct > 35 and to 6% 10 days after onset; it is similar in asymptomatic and symptomatic persons. Asymptomatic persons represent a source of transmissible virus.
All Keywords
【저자키워드】 COVID-19, SARS-CoV-2, coronavirus, respiratory virus, infectiousness, public health policy, 【초록키워드】 coronavirus disease, RT-PCR, virus, Asymptomatic, Viral load, cycle threshold, symptomatic, upper respiratory tract, Infectious virus, Decline, Mild-to-moderate, symptom onset, acute respiratory syndrome, analysed, persist, 【제목키워드】 RT-PCR, Duration, correlation, England, Cycle threshold value,
【저자키워드】 COVID-19, SARS-CoV-2, coronavirus, respiratory virus, infectiousness, public health policy, 【초록키워드】 coronavirus disease, RT-PCR, virus, Asymptomatic, Viral load, cycle threshold, symptomatic, upper respiratory tract, Infectious virus, Decline, Mild-to-moderate, symptom onset, acute respiratory syndrome, analysed, persist, 【제목키워드】 RT-PCR, Duration, correlation, England, Cycle threshold value,