Containment strategies and clinical management of coronavirus disease (COVID-19) patients during the current pandemic depend on reliable diagnostic PCR assays for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we compare 11 different RT-PCR test systems used in seven diagnostic laboratories in Germany in March 2020. While most assays performed well, we identified detection problems in a commonly used assay that may have resulted in false-negative test results during the first weeks of the pandemic.
All Keywords
【저자키워드】 COVID-19, SARS-CoV-2, diagnostic test, PCR, 【초록키워드】 coronavirus disease, coronavirus, pandemic, diagnostic, Laboratory, Germany, Patient, Clinical management, false-negative, Containment, RT-PCR test, acute respiratory syndrome, PCR assay, problem, while, Seven, performed, 【제목키워드】 Germany, Quantitative, detect, PCR-based assay,
【저자키워드】 COVID-19, SARS-CoV-2, diagnostic test, PCR, 【초록키워드】 coronavirus disease, coronavirus, pandemic, diagnostic, Laboratory, Germany, Patient, Clinical management, false-negative, Containment, RT-PCR test, acute respiratory syndrome, PCR assay, problem, while, Seven, performed, 【제목키워드】 Germany, Quantitative, detect, PCR-based assay,