We whole-genome sequenced 55 SARS-CoV-2 isolates from Germany to investigate SARS-CoV-2 outbreaks in 2020 in the Heinsberg district and Düsseldorf. While the genetic structure of the Heinsberg outbreak indicates a clonal origin, reflecting superspreading dynamics from mid-February during the carnival season, distinct viral strains were circulating in Düsseldorf in March, reflecting the city’s international links. Limited detection of Heinsberg strains in the Düsseldorf area despite geographical proximity may reflect efficient containment and contact-tracing efforts.
All Keywords
【저자키워드】 COVID-19, SARS-CoV-2, Nanopore, ARTIC, superspreading, Genomic epidemiology, Heinsberg, Düsseldorf, 【초록키워드】 Genetic, Germany, outbreak, International, strain, viral strain, circulating, while, whole-genome, sequenced, indicate, Limited, SARS-CoV-2 isolate, 【제목키워드】 Germany, independent, events, reflect,
【저자키워드】 COVID-19, SARS-CoV-2, Nanopore, ARTIC, superspreading, Genomic epidemiology, Heinsberg, Düsseldorf, 【초록키워드】 Genetic, Germany, outbreak, International, strain, viral strain, circulating, while, whole-genome, sequenced, indicate, Limited, SARS-CoV-2 isolate, 【제목키워드】 Germany, independent, events, reflect,