Accumulating evidence suggests that a patient subgroup with severe COVID-19 develops a cytokine release syndrome leading to capillary leakage and organ injury. Recent publications addressing therapy of cytokine storms recommended new extracorporeal therapies such as hemoadsorption. This case report describes a 59-year-old SARS-CoV-2-positive patient with severe ARDS. Due to severe hyperinflammation with concomitant hemodynamic instability and progressive renal failure, combination of continuous renal replacement and CytoSorb® hemoadsorption therapy was initiated. Treatment resulted immediately in a control of the hyperinflammatory response. Simultaneously, lung function continued to improve accompanied by profound hemodynamic stabilization. We report the successful utilization of CytoSorb® hemoadsorption in the treatment of a patient with SARS-CoV-2-induced cytokine storm syndrome.
【초록키워드】 Treatment, Cytokine storm, therapy, severe COVID-19, Cytokine storm syndrome, Case report, Cytokine release syndrome, hyperinflammation, Lung function, Patient, hemoadsorption, hemodynamic, Evidence, Combination, severe ARDS, organ injury, renal, hemodynamic instability, Hyperinflammatory, recent, extracorporeal therapy, patient subgroup, capillary leakage, IMPROVE, develop, initiated, accompanied, 【제목키워드】 storm, handle,