Abstract Despite being initially considered at higher risk for severe COVID‐19, sickle cell disease (SCD) patients have mostly presented clinical severity similar to the general population. As their vulnerability to become infected remains uncertain, we assessed the seroreactivity for SARS‐CoV‐2 to estimate the prevalence of infection and possible phenotypic and socioeconomic determinants for their contagion. Serologic evaluation was performed on 135 patients with an overall prevalence of 11%; positivity was associated with older age and use of public transportation. We speculate that social distancing instructions recommended by our clinic may have contributed to lower levels of infection, but potential protection factors need further investigation.
【초록키워드】 social distancing, Infection, COVID‐19, SARS‐CoV‐2, Prevalence, serologic, Patient, Older age, General population, disease, Clinical severity, Contagion, determinant, Factor, higher risk, phenotypic, Cell, SCD, was performed, contributed, remains uncertain, 【제목키워드】 social isolation, SARS‐CoV‐2, Cohort, disease, high risk, Effect, Cell,