Children have been described to show neurological symptoms in acute coronavirus disease 2019 (COVID-19) and multisystemic inflammatory syndrome in children (MIS-C). We present a 2-year-old boy’s clinical course of unilateral acute sixth nerve palsy in the context of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Onset of the palsy in the otherwise healthy boy occurred seven days after symptoms attributed to acute infection had subsided respectively 3 weeks after onset of respiratory symptoms. SARS-CoV-2 specific IgG was detected in serum as well as in cerebrospinal fluid. The patient showed a prolonged but self-limiting course with a full recovery after three and a half months. This case illustrates in a detailed chronological sequence that sixth cranial nerve involvement may occur as post-infectious, self-limiting complication of pediatric SARS-CoV-2-infection thus expanding the neurological spectrum of symptoms for children with COVID-19. Clinicians should be aware of the possibility of post-infectious sixth nerve palsy related to SARS-CoV-2-infection particularly in view of recent respiratory tract infection or confirmed cases of SARS-CoV-2-infection amongst the patient’s close contacts.
【저자키워드】 COVID-19, SARS-CoV-2, pediatric, anti-SARS-CoV-2 antibodies, sixth cranial nerve palsy, 【초록키워드】 coronavirus disease, IgG, coronavirus, children, Infection, respiratory tract infection, Symptom, MIS-C, serum, Clinical course, acute infection, Patient, Onset, cerebrospinal fluid, Inflammatory, neurological, respiratory symptoms, confirmed case, acute respiratory syndrome, sequence, syndrome, full recovery, multisystemic, Neurological symptom, Seven, Course, described, occurred, healthy, the patient, occur, children with COVID-19, cranial, 【제목키워드】 Child, palsy, nerve, Unilateral,