What transpires soon after inhaling Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the respiratory virus causing Coronavirus Disease 2019 (COVID-19)? Where does infection begin? What are the features of subsequent virus spread? How might host responses quickly contain infection? Two recently published manuscripts have evaluated infection in primary cultures of well-differentiated cells to address these questions and bring more light on the proviral and antiviral components operating during the initial days after SARS-CoV-2 exposure.
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【초록키워드】 coronavirus disease, severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, Coronavirus disease 2019, coronavirus, Antiviral, Infection, host response, severe acute respiratory syndrome Coronavirus, virus, coronavirus 2, Severe acute respiratory syndrome, respiratory virus, respiratory, host responses, acute respiratory syndrome coronavirus, manuscript, component, feature, Cell, initial, subsequent, evaluated, question, primary culture, 【제목키워드】 SARS-COV-2 infection, single-cell,
【초록키워드】 coronavirus disease, severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, Coronavirus disease 2019, coronavirus, Antiviral, Infection, host response, severe acute respiratory syndrome Coronavirus, virus, coronavirus 2, Severe acute respiratory syndrome, respiratory virus, respiratory, host responses, acute respiratory syndrome coronavirus, manuscript, component, feature, Cell, initial, subsequent, evaluated, question, primary culture, 【제목키워드】 SARS-COV-2 infection, single-cell,
코로나바이러스감염증-19(COVID-19)를 유발하는 호흡기 바이러스인 중증급성호흡기증후군 코로나바이러스 2(SARS-CoV-2)를 흡입한 직후 어떤 일이 발생합니까? 감염은 어디에서 시작됩니까? 후속 바이러스 확산의 특징은 무엇입니까? 호스트 응답에 감염이 신속하게 포함될 수 있는 방법은 무엇입니까? 최근에 출판된 두 개의 원고는 이러한 질문을 해결하고 SARS-CoV-2 노출 후 초기 며칠 동안 작동하는 프로바이러스 및 항바이러스 성분에 대해 더 많은 정보를 제공하기 위해 잘 분화된 세포의 1차 배양에서 감염을 평가했습니다.