This case series describes clinical course of three COVID-19 patients who presented with major thromboembolic events. Patient 1 is a 57-year-old male with asymptomatic COVID-19 who presented with a large left ventricular thrombus. His hospital course was complicated with a stroke. Patient 2 is a 71-year-old male with mild COVID-19 who presented with an acute stroke. Patient 3 is a 47-year-old male with severe COVID-19 who presented with a large pulmonary embolism. He died of a recurrent massive pulmonary embolism. This case series demonstrates that thromboembolic event can be the presenting feature of COVID-19 and can occur in the patients with asymptomatic or mild COVID-19. Diffuse endothelial injury and hypercoagulability play a pivotal role in recurrent thromboembolic events despite the anticoagulation. Therapeutic anticoagulation may be considered for severe COVID-19 patients and patients with important comorbidities or pre-existing endothelial dysfunction.
【저자키워드】 COVID-19, anticoagulation, Hypercoagulable state, Virchow’s Triad, Thromboembolic event, 【초록키워드】 severe COVID-19, stroke, hospital, Comorbidity, Endothelial dysfunction, Clinical course, Asymptomatic, male, Patient, Mild, Thrombus, endothelial injury, hypercoagulability, COVID-19 patient, Asymptomatic COVID-19, Thromboembolic events, diffuse, Course, died, the patient, case sery, occur, presenting, severe COVID-19 patient, ventricular, 【제목키워드】 clinical, Major,